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Host-Pathogen Coevolution and the Emergence of Broadly Neutralizing Antibodies in Chronic Infections
The vertebrate adaptive immune system provides a flexible and diverse set of molecules to neutralize pathogens. Yet, viruses such as HIV can cause chronic infections by evolving as quickly as the adaptive immune system, forming an evolutionary arms race. Here we introduce a mathematical framework to...
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| Publicado no: | PLoS Genet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4956326/ https://ncbi.nlm.nih.gov/pubmed/27442127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006171 |
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