The Drosophila Forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling

BACKGROUND: Forkhead transcription factors belonging to the FOXO subfamily are negatively regulated by protein kinase B (PKB) in response to signaling by insulin and insulin-like growth factor in Caenorhabditis elegans and mammals. In Drosophila, the insulin-signaling pathway regulates the size of c...

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Detalhes bibliográficos

Publicado no:	J Biol
Principais autores:	Jünger, Martin A, Rintelen, Felix, Stocker, Hugo, Wasserman, Jonathan D, Végh, Mátyás, Radimerski, Thomas, Greenberg, Michael E, Hafen, Ernst
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2003
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333403/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12908874/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1475-4924-2-20
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