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Secondary binding sites for heavily modified triplex forming oligonucleotides
In order to enhance DNA triple helix stability synthetic oligonucleotides have been developed that bear amino groups on the sugar or base. One of the most effective of these is bis-amino-U (B), which possesses 5-propargylamino and 2′-aminoethoxy modifications. Inclusion of this modified nucleotide n...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3333850/ https://ncbi.nlm.nih.gov/pubmed/22180535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1119 |
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