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Algorithms for optimizing cross-overs in DNA shuffling

BACKGROUND: DNA shuffling generates combinatorial libraries of chimeric genes by stochastically recombining parent genes. The resulting libraries are subjected to large-scale genetic selection or screening to identify those chimeras with favorable properties (e.g., enhanced stability or enzymatic ac...

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Détails bibliographiques
Auteurs principaux: He, Lu, Friedman, Alan M, Bailey-Kellogg, Chris
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3333841/
https://ncbi.nlm.nih.gov/pubmed/22536901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-S3-S3
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