Cyclic adenosine 3',5'-monophosphate inhibits the availability of arachidonate to prostaglandin synthetase in human platelet suspensions.
When thrombin is added to washed human platelets, one of its actions results in activation of a phospholipase that hydrolyzes arachidonic acid from phospholipids. The arachidonate is converted to the cyclic endoperoxides (prostaglandin G2 and prostaglandin H2) by fatty acid cyclo-oxygenase. These co...
সংরক্ষণ করুন:
| প্রকাশিত: | J Clin Invest |
|---|---|
| প্রধান লেখক: | , , , , , , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
American Society for Clinical Investigation
1977
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333381/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/190267/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108659 |
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