Oxidized Phospholipids are Present on Plasminogen, Affect Fibrinolysis and Increase Following Acute Myocardial Infarction

OBJECTIVES: To assess whether plasminogen, which is homologous to lipoprotein (a) [Lp(a)], contains pro-inflammatory oxidized phospholipids (OxPL) and whether this has clinical relevance. BACKGROUND: OxPL measured on apolipoprotein B-100 (OxPL/apoB), primarily reflecting OxPL on Lp(a), independently...

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Hauptverfasser: Leibundgut, Gregor, Arai, Kiyohito, Orsoni, Alexina, Yin, Huiyong, Scipione, Corey, Miller, Elizabeth R., Koschinsky, Marlys L., Chapman, M. John, Witztum, Joseph L., Tsimikas, Sotirios
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3333481/
https://ncbi.nlm.nih.gov/pubmed/22497821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2011.12.033
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