Irreversible deformation of the spectrin-actin lattice in irreversibly sickled cells.
Irreversibly sickled cells (ISC's) are circulating erythrocytes in patients with sickle cell disease that retain a sickled shape even when oxygenated. Evidence points to a membrane defect that prevents the return of these cells to the normal biconcave shape. The erythrocyte membrane protein spectrin...
Guardat en:
| Publicat a: | J Clin Invest |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
1976
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333259/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/965498/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108549 |
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