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Irreversible deformation of the spectrin-actin lattice in irreversibly sickled cells.

Irreversibly sickled cells (ISC's) are circulating erythrocytes in patients with sickle cell disease that retain a sickled shape even when oxygenated. Evidence points to a membrane defect that prevents the return of these cells to the normal biconcave shape. The erythrocyte membrane protein spe...

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Autori principali: Lux, S E, John, K M, Karnovsky, M J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1976
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC333259/
https://ncbi.nlm.nih.gov/pubmed/965498
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