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Irreversible deformation of the spectrin-actin lattice in irreversibly sickled cells.

Irreversibly sickled cells (ISC's) are circulating erythrocytes in patients with sickle cell disease that retain a sickled shape even when oxygenated. Evidence points to a membrane defect that prevents the return of these cells to the normal biconcave shape. The erythrocyte membrane protein spectrin...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
-д хэвлэсэн:J Clin Invest
Үндсэн зохиолчид: Lux, S E, John, K M, Karnovsky, M J
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: American Society for Clinical Investigation 1976
Нөхцлүүд:
Онлайн хандалт:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333259/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/965498/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108549
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