Irreversible deformation of the spectrin-actin lattice in irreversibly sickled cells.

Irreversibly sickled cells (ISC's) are circulating erythrocytes in patients with sickle cell disease that retain a sickled shape even when oxygenated. Evidence points to a membrane defect that prevents the return of these cells to the normal biconcave shape. The erythrocyte membrane protein spectrin...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Lux, S E, John, K M, Karnovsky, M J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1976
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333259/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/965498/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108549
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