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Resveratrol Prevents Endothelial Cells Injury in High-Dose Interleukin-2 Therapy against Melanoma

Immunotherapy with high-dose interleukin-2 (HDIL-2) is an effective treatment for patients with metastatic melanoma and renal cell carcinoma. However, it is accompanied by severe toxicity involving endothelial cell injury and induction of vascular leak syndrome (VLS). In this study, we found that re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guan, Hongbing, Singh, Narendra P., Singh, Udai P., Nagarkatti, Prakash S., Nagarkatti, Mitzi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331985/
https://ncbi.nlm.nih.gov/pubmed/22532866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035650
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