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Resveratrol (trans-3,5,4'-trihydroxystilbene) suppresses EL4 tumor growth by induction of apoptosis involving reciprocal regulation of SIRT1 and NF-κB

SCOPE: Understanding the molecular mechanisms through which natural products and dietary supplements exhibit anticancer properties is crucial and can lead to drug discovery and chemoprevention. The current study sheds new light on the mode of action of Resveratarol (RES), a plant-derived polyphenoli...

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Autori principali: Singh, Narendra P., Singh, Udai P., Hegde, Venkatesh L., Guan, Hongbing, Hofseth, Lorne, Nagarkatti, Mitzi, Nagarkatti, Prakash S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516994/
https://ncbi.nlm.nih.gov/pubmed/21520490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201000576
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