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Resveratrol Prevents Endothelial Cells Injury in High-Dose Interleukin-2 Therapy against Melanoma

Immunotherapy with high-dose interleukin-2 (HDIL-2) is an effective treatment for patients with metastatic melanoma and renal cell carcinoma. However, it is accompanied by severe toxicity involving endothelial cell injury and induction of vascular leak syndrome (VLS). In this study, we found that re...

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Detalhes bibliográficos
Main Authors: Guan, Hongbing, Singh, Narendra P., Singh, Udai P., Nagarkatti, Prakash S., Nagarkatti, Mitzi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331985/
https://ncbi.nlm.nih.gov/pubmed/22532866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035650
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