The facile synthesis of multifunctional PAMAM dendrimer conjugates through copper-free click chemistry

The facile conjugation of three azido modified functionalities, namely a therapeutic drug (methotrexate), a targeting moiety (folic acid), and an imaging agent (fluorescein) with a G5 PAMAM dendrimer scaffold with cyclooctyne molecules at the surface through copper-free click chemistry is reported....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Huang, Baohua, Kukowska-Latallo, Jolanta F., Tang, Shengzhuang, Zong, Hong, Johnson, Kali B., Desai, Ankur, Gordon, Chris L., Leroueil, Pascale R., Baker, James R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331967/
https://ncbi.nlm.nih.gov/pubmed/22480432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.03.052
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