The facile synthesis of multifunctional PAMAM dendrimer conjugates through copper-free click chemistry

The facile conjugation of three azido modified functionalities, namely a therapeutic drug (methotrexate), a targeting moiety (folic acid), and an imaging agent (fluorescein) with a G5 PAMAM dendrimer scaffold with cyclooctyne molecules at the surface through copper-free click chemistry is reported....

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Huang, Baohua, Kukowska-Latallo, Jolanta F., Tang, Shengzhuang, Zong, Hong, Johnson, Kali B., Desai, Ankur, Gordon, Chris L., Leroueil, Pascale R., Baker, James R.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331967/
https://ncbi.nlm.nih.gov/pubmed/22480432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.03.052
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki