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Progression from obesity to metabolic syndrome is associated with altered myocardial autophagy and apoptosis

OBJECTIVE: Transition from obesity to metabolic-syndrome (MetS) promotes cardiovascular diseases, but the underlying cardiac pathophysiological mechanisms are incompletely understood. We tested the hypothesis that development of insulin resistance (IR) and MetS is associated with impaired myocardial...

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Autors principals: Li, Zi-Lun, Woollard, John R., Ebrahimi, Behzad, Crane, John A., Jordan, Kyra L., Lerman, Amir, Wang, Shen-Ming, Lerman, Lilach O.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331917/
https://ncbi.nlm.nih.gov/pubmed/22383702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.244061
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