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Downregulation of doxorubicin-induced myocardial apoptosis accompanies postnatal heart maturation
Doxorubicin is a highly effective chemotherapeutic agent used for treating a wide spectrum of tumors, but its usage is limited because of its dose-dependent cardiotoxicity, especially in pediatric patients. Accumulating evidence indicates that caspase-dependent apoptosis contributes to the cardiotox...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3330803/ https://ncbi.nlm.nih.gov/pubmed/22328080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00844.2011 |
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