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Clathrin mediates endocytosis of progastrin and activates MAPKs: role of cell surface annexin A2

Cell-surface-associated annexin A2 (CS-ANXA2) is a nonconventional “receptor” for progastrin; expression levels of both are elevated in colon cancers, and downregulation of either reduces tumorigenic potential of cells. We recently reported internalization of progastrin in target cells. Here, mechan...

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Autors principals: Sarkar, Shubhashish, Kantara, Carla, Singh, Pomila
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330782/
https://ncbi.nlm.nih.gov/pubmed/22241862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00406.2011
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