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AnnexinA(2) mediates upregulation of NF-κ B, β-catenin, CD44 and DCAMKL+1 in response to progastrin in miceandHEK-293 cells
BACKGROUND & AIMS: Prograstrin induces proliferation in colon crypts by activating p65NF-κ B and β-catenin. We investigated whether Annexin A2 (AnxA2), a progastrin receptor, activates NF-κB and β-catenin in vivo. METHOD: ANXA2-null (ANXA2− /−) and wild-type (ANXA2+/+) mice were studied, along w...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031715/ https://ncbi.nlm.nih.gov/pubmed/20826156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.08.054 |
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