Insulin-like growth factors are more effective than progastrin in reversing proapoptotic effects of curcumin: critical role of p38MAPK

Progastrin and insulin-like growth factors (IGFs) stimulate hyperproliferation of intestinal epithelial cells (IECs) via endocrine/paracrine routes; hyperproliferation is a known risk factor for colon carcinogenesis. In the present study, inhibitory potency of curcumin in the presence or absence of...

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Detalhes bibliográficos
Main Authors: Singh, Pomila, Sarkar, Shubhashish, Umar, Shahid, Rengifo-Cam, William, Singh, Amar P., Wood, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Mucosal Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853304/
https://ncbi.nlm.nih.gov/pubmed/20133951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00497.2009
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