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Mitochondrial permeability transition in rat hepatocytes after anoxia/reoxygenation: role of Ca(2+)-dependent mitochondrial formation of reactive oxygen species
Onset of the mitochondrial permeability transition (MPT) is the penultimate event leading to lethal cellular ischemia-reperfusion injury, but the mechanisms precipitating the MPT after reperfusion remain unclear. Here, we investigated the role of mitochondrial free Ca(2+) and reactive oxygen species...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3330780/ https://ncbi.nlm.nih.gov/pubmed/22241863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00082.2011 |
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