Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study

BACKGROUND: In this prospective cohort study, we have undertaken a comprehensive evaluation of clinical parameters along with variation in 29 genes (including CYP2C9 and VKORC1) to identify factors determining interindividual variability in warfarin response. METHODS: Consecutive patients (n = 311)...

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Main Authors: Jorgensen, Andrea L., Al-Zubiedi, Sameh, Zhang, Jieying Eunice, Keniry, Andrew, Hanson, Anita, Hughes, Dyfrig A., van Eker, Diane, Stevens, Lisa, Hawkins, Karen, Toh, Cheng H., Kamali, Farhad, Daly, Ann K., Fitzmaurice, David, Coffey, Alison, Williamson, Paula R., Park, Brian Kevin, Deloukas, Panos, Pirmohamed, Munir
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330749/
https://ncbi.nlm.nih.gov/pubmed/19752777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283317ab5
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