Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study

BACKGROUND: In this prospective cohort study, we have undertaken a comprehensive evaluation of clinical parameters along with variation in 29 genes (including CYP2C9 and VKORC1) to identify factors determining interindividual variability in warfarin response. METHODS: Consecutive patients (n = 311)...

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主要な著者: Jorgensen, Andrea L., Al-Zubiedi, Sameh, Zhang, Jieying Eunice, Keniry, Andrew, Hanson, Anita, Hughes, Dyfrig A., van Eker, Diane, Stevens, Lisa, Hawkins, Karen, Toh, Cheng H., Kamali, Farhad, Daly, Ann K., Fitzmaurice, David, Coffey, Alison, Williamson, Paula R., Park, Brian Kevin, Deloukas, Panos, Pirmohamed, Munir
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330749/
https://ncbi.nlm.nih.gov/pubmed/19752777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283317ab5
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