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Functional interplay between p53 acetylation and H1.2 phosphorylation in p53-regulated transcription
Linker histone H1.2 has been shown to suppress p53-dependent transcription through the modulation of chromatin remodeling; however, little is known about the mechanisms governing the antagonistic effects of H1.2 in DNA damage response. Here we show that the repressive action of H1.2 on p53 function...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3330162/ https://ncbi.nlm.nih.gov/pubmed/22249259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.605 |
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