Significance of Urinary Full-Length and Ectodomain Forms of Megalin in Patients With Type 2 Diabetes

OBJECTIVE: Megalin, an endocytic receptor in proximal tubule cells, is involved in the mechanisms of albuminuria in diabetic nephropathy (DN). To develop efficient novel biomarkers associated with the pathogenesis of DN, we investigated urinary megalin excretion in type 2 diabetes. RESEARCH DESIGN A...

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Bibliografiset tiedot
Päätekijät: Ogasawara, Shinya, Hosojima, Michihiro, Kaseda, Ryohei, Kabasawa, Hideyuki, Yamamoto-Kabasawa, Keiko, Kurosawa, Hiroyuki, Sato, Hiroyoshi, Iino, Noriaki, Takeda, Tetsuro, Suzuki, Yoshiki, Narita, Ichiei, Yamagata, Kunihiro, Tomino, Yasuhiko, Gejyo, Fumitake, Hirayama, Yoshiaki, Sekine, Sakari, Saito, Akihiko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Diabetes Association 2012
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329833/
https://ncbi.nlm.nih.gov/pubmed/22410816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc11-1684
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