Low Prevalence of TP53 Mutations and MDM2 Amplifications in Pediatric Rhabdomyosarcoma

The tumor suppressor gene TP53 is the most commonly mutated gene in human cancer. The reported prevalence of mutations in rhabdomyosarcoma (RMS) varies widely, with recent larger studies suggesting that TP53 mutations in pediatric RMS may be extremely rare. Overexpression of MDM2 also attenuates p53...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Ognjanovic, Simona, Martel, Ghyslaine, Manivel, Carlos, Olivier, Magali, Langer, Erica, Hainaut, Pierre
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329663/
https://ncbi.nlm.nih.gov/pubmed/22550420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/492086
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker