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DISTINCT ROLES OF β1 MIDAS, ADMIDAS AND LIMBS CATION-BINDING SITES IN LIGAND RECOGNITION BY INTEGRIN α2β1

Integrin-ligand interactions are regulated in a complex manner by divalent cations, and previous studies have identified ligand-competent, stimulatory, and inhibitory cation-binding sites. In collagen-binding integrins, such as α2β1, ligand recognition takes place exclusively at the α subunit I doma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Valdramidou, Dimitra, Humphries, Martin J., Mould, A. Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329621/
https://ncbi.nlm.nih.gov/pubmed/18820259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802066200
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