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Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin alpha5 beta1.

The molecular mechanisms that regulate integrin-ligand binding are unknown; however, bivalent cations are essential for integrin activity. According to recent models of integrin tertiary structure, sites involved in ligand recognition are located on the upper face of the seven-bladed beta-propeller...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Mould, A P, Garratt, A N, Puzon-McLaughlin, W, Takada, Y, Humphries, M J
פורמט: Artigo
שפה:Inglês
יצא לאור: 1998
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219423/
https://ncbi.nlm.nih.gov/pubmed/9560310
תגים: הוספת תג
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