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CXCL12 and [N33A]CXCL12 in 5637 and HeLa Cells: Regulating HER1 Phosphorylation via Calmodulin/Calcineurin

In the human neoplastic cell lines 5637 and HeLa, recombinant CXCL12 elicited, as expected, downstream signals via both G-protein-dependent and β-arrestin-dependent pathways responsible for inducing a rapid and a late wave, respectively, of ERK1/2 phosphorylation. In contrast, the structural variant...

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Detalhes bibliográficos
Main Authors: Rigo, Antonella, Gottardi, Michele, Damiani, Ernesto, Bonifacio, Massimiliano, Ferrarini, Isacco, Mauri, Pierluigi, Vinante, Fabrizio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329496/
https://ncbi.nlm.nih.gov/pubmed/22529914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034432
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