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Propylthiouracil Is Teratogenic in Murine Embryos

BACKGROUND: Hyperthyroidism during pregnancy is treated with the antithyroid drugs (ATD) propylthiouracil (PTU) and methimazole (MMI). PTU currently is recommended as the drug of choice during early pregnancy. Yet, despite widespread ATD use in pregnancy, formal studies of ATD teratogenic effects ha...

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Detalhes bibliográficos
Main Authors: Benavides, Valeria C., Mallela, Murali K., Booth, Carmen J., Wendler, Christopher C., Rivkees, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329451/
https://ncbi.nlm.nih.gov/pubmed/22529993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035213
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