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Propylthiouracil Is Teratogenic in Murine Embryos

BACKGROUND: Hyperthyroidism during pregnancy is treated with the antithyroid drugs (ATD) propylthiouracil (PTU) and methimazole (MMI). PTU currently is recommended as the drug of choice during early pregnancy. Yet, despite widespread ATD use in pregnancy, formal studies of ATD teratogenic effects ha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Benavides, Valeria C., Mallela, Murali K., Booth, Carmen J., Wendler, Christopher C., Rivkees, Scott A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329451/
https://ncbi.nlm.nih.gov/pubmed/22529993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035213
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