Propylthiouracil Is Teratogenic in Murine Embryos

BACKGROUND: Hyperthyroidism during pregnancy is treated with the antithyroid drugs (ATD) propylthiouracil (PTU) and methimazole (MMI). PTU currently is recommended as the drug of choice during early pregnancy. Yet, despite widespread ATD use in pregnancy, formal studies of ATD teratogenic effects ha...

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Главные авторы: Benavides, Valeria C., Mallela, Murali K., Booth, Carmen J., Wendler, Christopher C., Rivkees, Scott A.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329451/
https://ncbi.nlm.nih.gov/pubmed/22529993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035213
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