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Role of Direct Repeat and Stem-Loop Motifs in mtDNA Deletions: Cause or Coincidence?
Deletion mutations within mitochondrial DNA (mtDNA) have been implicated in degenerative and aging related conditions, such as sarcopenia and neuro-degeneration. While the precise molecular mechanism of deletion formation in mtDNA is still not completely understood, genome motifs such as direct repe...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3329436/ https://ncbi.nlm.nih.gov/pubmed/22529999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035271 |
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