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NR2F1 disrupts synergistic activation of the MTTP gene transcription by HNF-4α and HNF-1α

Regulation of microsomal triglyceride transfer protein (MTP) expression mainly occurs at the transcriptional level. We have previously shown that MTTP gene expression was repressed in nondifferentiated intestinal cells by nuclear receptor 2 family 1 (NR2F1). However, mechanisms involved in the repre...

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Hlavní autoři: Dai, Kezhi, Hussain, M. Mahmood
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329389/
https://ncbi.nlm.nih.gov/pubmed/22357705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M025130
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