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Activation of Wnt3a signaling stimulates intestinal epithelial repair by promoting c-Myc-regulated gene expression

In response to mucosal injury, epithelial cells modify the patterns of expressed genes to repair damaged tissue rapidly. Our previous studies have demonstrated that the transcription factor c-Myc is necessary for stimulation of epithelial cell renewal during mucosal healing, but the up-stream signal...

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Hlavní autoři: Liu, Lan, Rao, Jaladanki N., Zou, Tongtong, Xiao, Lan, Smith, Alexis, Zhuang, Ran, Turner, Douglas J., Wang, Jian-Ying
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328905/
https://ncbi.nlm.nih.gov/pubmed/21975427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00341.2011
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