Polyamines regulate intestinal epithelial restitution through TRPC1-mediated Ca(2+) signaling by differentially modulating STIM1 and STIM2

Early epithelial restitution occurs as a consequence of intestinal epithelial cell (IEC) migration after wounding, and its defective regulation is implicated in various critical pathological conditions. Polyamines stimulate intestinal epithelial restitution, but their exact mechanism remains unclear...

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Autori principali: Rao, Jaladanki N., Rathor, Navneeta, Zhuang, Ran, Zou, Tongtong, Liu, Lan, Xiao, Lan, Turner, Douglas J., Wang, Jian-Ying
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423028/
https://ncbi.nlm.nih.gov/pubmed/22592407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00120.2012
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