Temozolomide in aggressive pituitary adenomas and carcinomas

Temozolomide is an alkylating agent used in the treatment of gliomas and, more recently, aggressive pituitary adenomas and carcinomas. Temozolomide methylates DNA and, thereby, has antitumor effects. O(6)-methylguanine-DNA methyltransferase, a DNA repair enzyme, removes the alkylating adducts that a...

詳細記述

保存先:
書誌詳細
主要な著者: Ortiz, Leon D., Syro, Luis V., Scheithauer, Bernd W., Rotondo, Fabio, Uribe, Humberto, Fadul, Camilo E., Horvath, Eva, Kovacs, Kalman
フォーマット: Artigo
言語:Inglês
出版事項: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2012
主題:
Review
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328813/
https://ncbi.nlm.nih.gov/pubmed/22584716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6061/clinics/2012(Sup01)20
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