Temozolomide in aggressive pituitary adenomas and carcinomas

Temozolomide is an alkylating agent used in the treatment of gliomas and, more recently, aggressive pituitary adenomas and carcinomas. Temozolomide methylates DNA and, thereby, has antitumor effects. O(6)-methylguanine-DNA methyltransferase, a DNA repair enzyme, removes the alkylating adducts that a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ortiz, Leon D., Syro, Luis V., Scheithauer, Bernd W., Rotondo, Fabio, Uribe, Humberto, Fadul, Camilo E., Horvath, Eva, Kovacs, Kalman
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2012
Gaiak:
Review
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328813/
https://ncbi.nlm.nih.gov/pubmed/22584716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6061/clinics/2012(Sup01)20
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