Development of novel inhibitor probes of DNA polymerase III based on dGTP analogs of the HPUra type: base, nucleoside and nucleotide derivatives of N2-(3,4-dichlorobenzyl)guanine.

6-(p-Hydroxyphenylhydrazino)uracil (H2-HPUra) is a selective and potent inhibitor of the replication-specific class III DNA polymerase (pol III) of Gr+ bacteria. Although formally a pyrimidine, H2-HPUra derives its inhibitory activity from its specific capacity to mimic the purine nucleotide, dGTP....

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Butler, M M, Dudycz, L W, Khan, N N, Wright, G E, Brown, N C
Médium: Artigo
Jazyk:Inglês
Vydáno: 1990
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC332876/
https://ncbi.nlm.nih.gov/pubmed/2259629
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky