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Targeting frameshifting in the human immunodeficiency virus
INTRODUCTION: HIV-1 uses a programmed -1 ribosomal frameshift to generate Gag-Pol, the precursor of its enzymes, when its full-length mRNA is translated by the ribosomes of the infected cells. This change in the reading frame occurs at a so-called slippery sequence that is followed by a specific sec...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328590/ https://ncbi.nlm.nih.gov/pubmed/22404160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2012.665879 |
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