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Selection of peptides interfering with a ribosomal frameshift in the human immunodeficiency virus type 1

The human immunodeficiency virus of type 1 (HIV-1) uses a programmed -1 ribosomal frameshift to produce the precursor of its enzymes, and changes in frameshift efficiency reduce replicative fitness of the virus. We used a fluorescent two-reporter system to screen for peptides that reduce HIV-1 frame...

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Detalhes bibliográficos
Main Authors: Dulude, Dominic, Théberge-Julien, Gabriel, Brakier-Gingras, Léa, Heveker, Nikolaus
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327360/
https://ncbi.nlm.nih.gov/pubmed/18367719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.887008
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