Essential role of EBF1 in the generation and function of distinct mature B cell types

The transcription factor EBF1 is essential for lineage specification in early B cell development. In this study, we demonstrate by conditional mutagenesis that EBF1 is required for B cell commitment, pro–B cell development, and subsequent transition to the pre–B cell stage. Later in B cell developme...

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Detalhes bibliográficos
Main Authors: Vilagos, Bojan, Hoffmann, Mareike, Souabni, Abdallah, Sun, Qiong, Werner, Barbara, Medvedovic, Jasna, Bilic, Ivan, Minnich, Martina, Axelsson, Elin, Jaritz, Markus, Busslinger, Meinrad
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328360/
https://ncbi.nlm.nih.gov/pubmed/22473956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112422
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