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Essential role of EBF1 in the generation and function of distinct mature B cell types
The transcription factor EBF1 is essential for lineage specification in early B cell development. In this study, we demonstrate by conditional mutagenesis that EBF1 is required for B cell commitment, pro–B cell development, and subsequent transition to the pre–B cell stage. Later in B cell developme...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328360/ https://ncbi.nlm.nih.gov/pubmed/22473956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112422 |
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