Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy

Cockayne syndrome (CS) is a devastating autosomal recessive disease characterized by neurodegeneration, cachexia, and accelerated aging. 80% of the cases are caused by mutations in the CS complementation group B (CSB) gene known to be involved in DNA repair and transcription. Recent evidence indicat...

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Autors principals: Scheibye-Knudsen, Morten, Ramamoorthy, Mahesh, Sykora, Peter, Maynard, Scott, Lin, Ping-Chang, Minor, Robin K., Wilson III, David M., Cooper, Marcus, Spencer, Richard, de Cabo, Rafael, Croteau, Deborah L., Bohr, Vilhelm A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328359/
https://ncbi.nlm.nih.gov/pubmed/22473955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111721
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