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PKA/AKAP1 and PP2A/Bβ2 Regulate Neuronal Morphogenesis via Drp1 Phosphorylation and Mitochondrial Bioenergetics

Mitochondrial shape is determined by fission and fusion reactions, perturbation of which can contribute to neuronal injury and disease. Mitochondrial fission is catalyzed by dynamin-related protein 1 (Drp1), a large GTPase of the dynamin family that is highly expressed in neurons and regulated by va...

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Detalles Bibliográficos
Main Authors: Dickey, Audrey S., Strack, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328351/
https://ncbi.nlm.nih.gov/pubmed/22049414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3159-11.2011
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