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Classification of Scaffold Hopping Approaches
The general goal of drug discovery is to identify novel compounds that are active against a preselected biological target with acceptable pharmacological properties defined by marketed drugs. Scaffold hopping has been widely applied by medicinal chemists to discover equipotent compounds with novel b...
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| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328312/ https://ncbi.nlm.nih.gov/pubmed/22056715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2011.10.024 |
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