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Classification of Scaffold Hopping Approaches
The general goal of drug discovery is to identify novel compounds that are active against a preselected biological target with acceptable pharmacological properties defined by marketed drugs. Scaffold hopping has been widely applied by medicinal chemists to discover equipotent compounds with novel b...
שמור ב:
| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328312/ https://ncbi.nlm.nih.gov/pubmed/22056715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2011.10.024 |
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