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Enforced Expression of PPP1R13L Increases Tumorigenesis and Invasion Through p53-Dependent and p53-Independent Mechanisms

PPP1R13L was initially identified as a protein that binds to the NF-κB subunit p65/RelA and inhibits its transcriptional activity. It also binds p53 and inhibits its action. One set of experimental findings based on overexpression of PPP1R13L indicates that PPP1R13L blocks apoptosis. Another set of...

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Detalhes bibliográficos
Main Authors: Laska, Magdalena J., Lowe, Scott W., Zender, Lars, Hearn, Stephen, Vogel, Ulla, Jensen, Uffe B., Bric, Anka, Nexø, Bjørn A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328301/
https://ncbi.nlm.nih.gov/pubmed/19263435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20528
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