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Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis.
Dysregulated cell-cell adhesion plays a critical role in epithelial cancer development. Studies of human and mouse cancers have indicated that loss of adhesion complexes known as adherens junctions contributes to tumor progression and metastasis. In contrast, little is known regarding the role of th...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science (PLoS)
2010-10-01
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| シリーズ: | PLoS Genetics |
| オンライン･アクセス: | http://europepmc.org/articles/PMC2958815?pdf=render |
| タグ: |
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