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Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis.

Dysregulated cell-cell adhesion plays a critical role in epithelial cancer development. Studies of human and mouse cancers have indicated that loss of adhesion complexes known as adherens junctions contributes to tumor progression and metastasis. In contrast, little is known regarding the role of th...

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Detaylı Bibliyografya
Asıl Yazarlar: Veronica G Beaudry, Dadi Jiang, Rachel L Dusek, Eunice J Park, Stevan Knezevich, Katie Ridd, Hannes Vogel, Boris C Bastian, Laura D Attardi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2010-10-01
Seri Bilgileri:PLoS Genetics
Online Erişim:http://europepmc.org/articles/PMC2958815?pdf=render
Etiketler: Etiketle
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