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HIV-1 Nef interaction influences the ATP-binding site of the Src-family kinase, Hck
BACKGROUND: Nef is an HIV-1 accessory protein essential for viral replication and AIDS progression. Nef interacts with a multitude of host cell signaling partners, including members of the Src kinase family. Nef preferentially activates Hck, a Src-family kinase (SFK) strongly expressed in macrophage...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328272/ https://ncbi.nlm.nih.gov/pubmed/22420777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6769-12-1 |
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