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Quantitation of integrin receptor agonism by fluorescence lifetime imaging

Both spatiotemporal analyses of adhesion signalling and the development of pharmacological inhibitors of integrin adhesion receptors currently suffer from the lack of an assay to measure integrin-effector binding and the response of these interactions to agonists. Here, we have expressed integrin-GF...

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Autori principali: Parsons, Maddy, Messent, Anthea J., Humphries, Jonathan D., Deakin, Nicholas O., Humphries, Martin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328206/
https://ncbi.nlm.nih.gov/pubmed/18216331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.018440
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